Featured Publications & Cover Galleries from Tao Lab

• He Z, Chen W, Hu K, Luo Y, Zeng W, He X, Li T, Ouyang J, Li Y, Xie L, Zhang Y, Xu Q, Yang S, Guo M, Zou W, Li Y, Huang L, Chen L, Zhang X, Saiding Q, Wang R, Zhang M, Kong N, Xie T, Song X, Tao W*. Resolvin D1 delivery to lesional macrophages using antioxidative black phosphorus nanosheets for atherosclerosis treatment. Nature Nanotechnology 2024, doi: 10.1038/s41565-024-01687-1.

• Li Y, Chen W, Kang Y, Zhen X, Zhou Z, Liu C, Chen S, Huang X, Liu H, Koo S, Kong N, Ji X, Xie T, Tao W*. Nanosensitizer-mediated augmentation of sonodynamic therapy efficacy and antitumor immunity. Nature Communications 2023, 14: 6973.

• Tang Z, You X, Xiao Y, Chen W, Li Y, Huang X, Liu H, Xiao F, Liu C, Koo S, Kong N, Tao W*. Inhaled mRNA nanoparticles dual-targeting cancer cells and macrophages in the lung for effective transfection. Proceedings of the National Academy of Sciences USA 2023, 120(44): e2304966120 (PNAS Direct Submission).

• Chen S, Huang X, Xue Y, Álvarez-Benedi E, Shi Y, Chen W, Koo S, Siegwart D, Dong Y, Tao W*. Nanotechnology-based mRNA vaccines. Nature Reviews Methods Primers 2023, 3: 63.

• Liu C, Shi Q, Huang X, Koo S, Kong N, Tao W*. mRNA-based cancer therapeutics. Nature Reviews Cancer 2023, 23(8): 526-543.

• Huang X, Kong N, Zhang X, Cao Y, Langer R, Tao W*. The landscape of mRNA nanomedicine. Nature Medicine 2022, 28(11): 2273–2287. 

• Huang X, Kon E, Han X, Zhang X, Kong N, Mitchell M, Peer D, Tao W*. Nanotechnology-based strategies against SARS-CoV-2 variants. Nature Nanotechnology 2022, 17(10): 1027–1037.

• Kong N, Zhang R, Wu G, Sui X, Wang J, Kim NY, Blake S, De D, Xie T, Cao Y, Tao W*. Intravesical Delivery of KDM6A-mRNA via Mucoadhesive Nanoparticles Inhibits the Metastasis of Bladder Cancer. Proceedings of the National Academy of Sciences USA 2022, 119(7): e2112696119 (PNAS Direct Submission).

• Huang X, Liu C, Kong N, Xiao Y, Yurdagul A, Tabas I, Tao W*. Synthesis of siRNA nanoparticles to silence plaque-destabilizing gene in atherosclerotic lesional macrophages. Nature Protocols 2022, 17(3): 748–780.

• Chen W, Schilperoort M, Cao Y, Shi J, Tabas I, Tao W*. Macrophage-Targeted Nanomedicine for Diagnosis and Treatment of Atherosclerosis. Nature Reviews Cardiology 2022, 19(4): 228–249.

• Ji X, Ge L, Liu C, Tang Z, Xiao Y, Chen W, Lei Z, Gao W, Blake S, De D, Shi B, Zeng X, Kong N, Zhang X, Tao W*. Capturing functional two-dimensional nanosheets from sandwich-structure vermiculite for cancer theranostics. Nature Communications 2021, 12: 1124.

• Ouyang J, Ji X, Zhang X, Feng C, Tang Z, Kong N, Xie A, Wang J, Sui X, Deng L, Liu Y, Kim JS, Cao Y, Tao W*. In situ sprayed NIR-responsive, analgesic black phosphorus-based gel for diabetic ulcer treatment. Proceedings of the National Academy of Sciences USA 2020, 117(46): 28667-28677 (PNAS Direct Submission).

• Tang Z, Kong N, Zhang X, Liu Y, Hu P, Mou S, Liljeström P, Shi J, Tan W, Kim JS, Cao Y, Langer R, Leong K, Farokhzad OC, Tao W*. A materials science perspective on tackling COVID-19. Nature Reviews Materials 2020, 5(11): 847-860.

Selected Publications by Years

2024

85. He Z, Chen W, Hu K, Luo Y, Zeng W, He X, Li T, Ouyang J, Li Y, Xie L, Zhang Y, Xu Q, Yang S, Guo M, Zou W, Li Y, Huang L, Chen L, Zhang X, Saiding Q, Wang R, Zhang M, Kong N, Xie T, Song X, Tao W*. Resolvin D1 delivery to lesional macrophages using antioxidative black phosphorus nanosheets for atherosclerosis treatment. Nature Nanotechnology 2024, doi: 10.1038/s41565-024-01687-1.

84. Zhen X, Li Y, Yuan W, Zhang T, Li M, Huang J, Kong N, Xie X, Wang S, Tao W*. Biointerface-Engineered Hybrid Nanovesicles for Targeted Reprogramming of Tumor Microenvironment. Advanced Materials 2024, doi: 10.1002/adma.202401495.

83. Shi Y, Zhen X, Zhang Y, Li Y, Koo S, Saiding Q, Kong N, Liu G, Chen W, Tao W*. Chemically Modified Platforms for Better RNA Therapeutics. Chemical Reviews 2024, 124(3): 929–1033.

82. Deng B, Liu S, Wang Y, Ali B, Kong N, Xie T, Koo S, Ouyang J, Tao W*. Oral Nanomedicine: Challenges and Opportunities. Advanced Materials 2024, 36(6): 2306081.

81. Ding Q, Li Y, Xu X, Li B, Saiding Q, Gu M, Tao W*, Tang BZ, Kim JS. Diverse Interactions between AIEgens and Biomolecules/Organisms: Advancing from Strategic Design to Precision Theranostics. Chem (Cell Press) 2024, in press.

80. Saiding Q, Qin D, An S, Patel D, Khan M, Kong N, Tao W*. Therapeutic nucleic acids in regenerative medicine and tissue repair. Nano Research 2024, doi: 10.1007/s12274-024-6776-1. (Invited ArticleNano Research Award Special Issue to honor the significant achievements of Dr. Robert Langer)

79. Zhang Y, Shi Y, Khan M, Xiao F, Chen W, Tao W*, Yao K, Kong N. Ocular RNA nanomedicine: engineered delivery nanoplatforms in treating eye diseases. Trends in Biotechnology (Cell Press) 2024, 10.1016/j.tibtech.2024.05.002. (Invited Article)

2023

78. Li Y, Chen W, Kang Y, Zhen X, Zhou Z, Liu C, Chen S, Huang X, Liu H, Koo S, Kong N, Ji X, Xie T, Tao W*. Nanosensitizer-mediated augmentation of sonodynamic therapy efficacy and antitumor immunity. Nature Communications 2023, 14: 6973. (Highlighted in the "Biomedical applications for nanotechnologies" Collection)

77. Tang Z, You X, Xiao Y, Chen W, Li Y, Huang X, Liu H, Xiao F, Liu C, Koo S, Kong N, Tao W*. Inhaled mRNA nanoparticles dual-targeting cancer cells and macrophages in the lung for effective transfection. Proceedings of the National Academy of Sciences USA 2023, 120(44): e2304966120 (PNAS Direct Submission).

76. Saiding Q, Zhang Z, Chen S, Xiao F, Chen Y, Li Y, Zhen X, Khan M, Chen W, Koo S, Kong N, Tao W*. Nano-bio interactions in mRNA nanomedicine: Challenges and opportunities for targeted mRNA delivery. Advanced Drug Delivery Reviews 2023, 203: 115116. (Invited Article)

75. Chen S, Huang X, Xue Y, Álvarez-Benedi E, Shi Y, Chen W, Koo S, Siegwart D, Dong Y, Tao W*. Nanotechnology-based mRNA vaccines. Nature Reviews Methods Primers 2023, 3: 63. (Highlighted in the "Nobel Prize in Physiology or Medicine 2023" Collection)

74. Liu C, Shi Q, Huang X, Koo S, Kong N, Tao W*. mRNA-based cancer therapeutics. Nature Reviews Cancer 2023, 23(8): 526-543. (Highlighted in the "Nobel Prize in Physiology or Medicine 2023" Collection)

73. Zhang X, Wang T, Zhang Z, Liu H, Li L, Wang A, Ouyang J, Xie T, Zhang L, Xue J, Tao W*. Electrical Stimulation System Based on Electroactive Biomaterials for Bone Tissue Engineering. Materials Today 2023, 68: 177-203. (Highlighted Paper; Front Cover Paper)

72. Ouyang J, Deng B, Zou B, Li Y, Bu Q, Tian Y, Chen M, Chen W, Kong N, Chen T, Tao W*. Oral hydrogel microbeads-mediated in situ synthesis of selenoproteins for regulating intestinal immunity and microbiota. Journal of the American Chemical Society 2023, 145(22): 12193–12205. (Cover Paper)

71. Yu L, Yu M, Chen W, Sun S, Huang W, Wang T, Peng Z, Luo Z, Fang Y, Li Y, Deng Y, Wu M, Tao W*. In situ separable nanovaccines with stealthy bioadhesive capability for durable cancer immunotherapy. Journal of the American Chemical Society 2023, 145(15): 8375–8388. (Cover Paper; Web of Science Highly Cited Paper)

70. Liu H, Chen W, Wu G, Zhou J, Liu C, Tang Z, Huang X, Gao J, Xiao Y, Kong N, Joshi N, Cao Y, Abdi R, Tao W*. Glutathione-scavenging nanoparticle-mediated PROTACs delivery for targeted protein degradation and amplified antitumor effects. Advanced Science 2023, 10(16): 2207439.

69. Zhang X, Li Q, Li L, Ouyang J, Wang T, Chen J, Hu X, Ao Y, Qin D, Zhang L, Xue J, Cheng J, Tao W*. Bioinspired Mild Photothermal Effect-Reinforced Multifunctional Fiber Scaffolds Promote Bone Regeneration. ACS Nano 2023, 17(7): 6466–6479.

68. Ouyang J, Zhang Z, Deng B, Liu J, Wang L, Liu H, Koo S, Chen S, Li Y, Yaremenko AV , Huang X, Chen W, Lee Y, Tao W*. Oral drug delivery platforms for biomedical applications. Materials Today 2023, 62: 296-326. (Invited ArticleRising Star Award - Highlighted Paper; Web of Science Highly Cited Paper)

67. Zhang P, Xiao Y, Sun X, Lin X, Koo S, Yaremenko AV, Qin D, Kong N, Farokhzad OC, Tao W*. Cancer Nanomedicine Towards Clinical Translation: Obstacles, Opportunities, and Future Prospects. Med (Cell Press) 2023, 4(3): 147-167. (Invited Article)

66. Chen Y, Qin D, Zou J, Li X, Guo X, Tang Y, Liu C, Chen W, Kong N, Zhang C, Tao W*. Living Leukocyte-Based Drug Delivery Systems. Advanced Materials 2023, 35(17): 2207787. (Front Cover Paper)

65. Chen W, Li Y, Liu C, Kang Y, Qin D, Chen S, Zhou J, Liu H, Ferdows BE, Patel DN, Huang X, Koo S, Kong N, Ji X, Cao Y, Tao W*, Xie T. In situ Engineering of Tumor-Associated Macrophages via a Nanodrug-Delivering-Drug (β-Elemene@Stanene) Strategy for Enhanced Cancer Chemo-Immunotherapy. Angewandte Chemie International Edition 2023, 62(41): e202308413. (Angew. Chem. VIP and Front Cover Paper)

2022

64. Huang X, Kong N, Zhang X, Cao Y, Langer R, Tao W*. The landscape of mRNA nanomedicine. Nature Medicine 2022, 28(11): 2273–2287. (Featured article by Nature Medicine; Highlighted in the "Nobel Prize in Physiology or Medicine 2023" Collection; Web of Science Hot Paper | Highly Cited Paper)

63. Huang X, Kon E, Han X, Zhang X, Kong N, Mitchell M, Peer D, Tao W*. Nanotechnology-based strategies against SARS-CoV-2 variants. Nature Nanotechnology 2022, 17(10): 1027–1037. (Featured article by Nature Nanotechnology; Highlighted in the "Progress towards the Sustainable Development Goals" Collection)

62. Wang D, Feng C, Xiao Z, Huang C, Chen Z, Fang W, Ma X, Wang X, Luo L, Hu K, Tao W*. Therapeutic hydrogel for enhanced immunotherapy: A powerful combination of MnO2 nanosheets and vascular disruption. Nano Today 2022, 47: 101673.

61. Kang Y, Zhang H, Chen L, Dong J, Yao B, Yuan X, Qin D, Yaremenko A, Liu C, Feng C, Ji X, Tao W*. The marriage of Xenes and Hydrogels: Fundamentals, Applications, and Outlook. The Innovation (Cell Press) 2022, 3(6): 100327. (Invited Article)

60. Ouyang J, Chen W, Tao W*. Design of application-optimized hydrogels based on a swollen polymer network model. Matter (Cell Press) 2022, 5(8): 2471-2473.

59. Yi Y, Yu M, Feng C, Hao H, Zeng W, Lin C, Chen H, Lv F, Zhu D, Ji X, Mei L, Wu M, Tao W*. Transforming "Cold" Tumors into "Hot" Ones via Tumor Microenvironment-Responsive siRNA Micelleplexes for Enhanced Immunotherapy. Matter (Cell Press) 2022, 5(7): 2285-2305.

58. Ouyang J, Xie A, Zhou J, Liu R, Wang L, Liu H, Kong N, Tao W*. Minimally invasive nanomedicine: nanotechnology in photo-/ultrasound-/radiation-/magnetism-mediated therapy and imaging. Chemical Society Reviews 2022, 51(12): 4996–5041. (Invited ArticleEmerging Investigator Award Collection; Web of Science Hot Paper | Highly Cited Paper)

57. Xiao Y, Tang Z, Huang X, Chen W, Zhou J, Liu H, Liu C, Kong N, Tao W*. Emerging mRNA technologies: Delivery strategies and biomedical applications. Chemical Society Reviews 2022, 51(10): 3828-3845. (Front Cover Paper; Web of Science Highly Cited Paper)

56. Kong N, Zhang R, Wu G, Sui X, Wang J, Kim NY, Blake S, De D, Xie T, Cao Y, Tao W*. Intravesical Delivery of KDM6A-mRNA via Mucoadhesive Nanoparticles Inhibits the Metastasis of Bladder Cancer. Proceedings of the National Academy of Sciences USA 2022, 119(7): e2112696119 (PNAS Direct Submission). (Front Cover Paper; Web of Science Highly Cited PaperHighlighted: Nature Medicine 2022, 28(6): 1100-1102.

55. Tao W*, Peppas NA. Robotic pills for gastrointestinal-tract-targeted oral mRNA delivery. Matter (Cell Press) 2022, 5(3): 775-777. (Invited Article)

54. Zhang Z, Zhou J, Liu C, Zhang J, Shibata Y, Kong N, Corbo C, Harris MB, Tao W*. Emerging Biomimetic Nanotechnology in Orthopedic Diseases: Progress, Challenges, and Opportunities. Trends in Chemistry (Cell Press) 2022, 4(5): 420-436. (Invited Article)

53. Chen W, Tao W*. Precise Control of the Structure of Synthetic Hydrogel Networks for Precision Medicine Applications. Matter (Cell Press) 2022, 5(1): 18-19. (Invited Article)

52. Huang X, Liu C, Kong N, Xiao Y, Yurdagul A, Tabas I, Tao W*. Synthesis of siRNA nanoparticles to silence plaque-destabilizing gene in atherosclerotic lesional macrophages. Nature Protocols 2022, 17(3): 748–780. (Featured article by Nature Protocols; Web of Science Highly Cited Paper)

51. Chen W, Schilperoort M, Cao Y, Shi J, Tabas I, Tao W*. Macrophage-Targeted Nanomedicine for Diagnosis and Treatment of Atherosclerosis. Nature Reviews Cardiology 2022, 19(4): 228–249. (Cover Featured; Web of Science Highly Cited Paper; Highlighted in the "Mechanisms of atherosclerosis" Series of articles from Nature Reviews Cardiology)

50. Zhao M, Mi D, Ferdows BE, Li Y, Wang R, Li J, Patel D, Kong N, Shi S, Tao W*. State-of-the-art nanotechnologies for the detection, recovery, analysis and elimination of liquid biopsy components in cancer. Nano Today 2022, 42: 101361.

49. Ji X, Tang Z, Liu H, Kang Y, Chen L, Dong J, Chen W, Kong N, Tao W*, Xie T. Nanoheterojunction-mediated thermoelectric strategy for cancer surgical adjuvant treatment and β-elemene combination therapy. Advanced Materials 2023, 35(8): 2207391.

48. Ouyang J, Rao S, Liu R, Wang L, Chen W, Tao W*, Kong N. 2D Materials-based Nanomedicine: From Discovery to Applications. Advanced Drug Delivery Reviews 2022, 185: 114268. (Invited Article)

47. Zhang D, Zhong D, Ouyang J, He J, Qi Y, Chen W, Zhang X, Tao W*, Zhou M. Microalgae-based oral microcarriers for gut microbiota homeostasis and intestinal protection in cancer radiotherapy. Nature Communications 2022, 13: 1413. (Web of Science Highly Cited Paper)

46. Jangili P, Kong N, Kim JH, Zhou J, Liu H, Zhang X, Tao W*, Kim JS. DNA-Damage-Response-Targeting Mitochondria-Activated Multifunctional Prodrug Strategy for Self-defensive Tumor Therapy. Angewandte Chemie International Edition 2022, 61(16): e202117075. (Angew. Chem. VIP and Front Cover Paper)

2021

45. Huang X, Wu G, Liu C, Hua X, Tang Z, Xiao Y, Chen W, Zhou J, Kong N, Huang P, Shi J, Tao W*. Intercalation-driven Formation of siRNA Nanogels for Cancer Therapy. Nano Letters 2021, 21(22): 9706-9714.

44. Zhong D, Zhang D, Chen W, He J, Ren C, Zhang X, Kong N, Tao W*, Zhou M. Orally Deliverable Strategy Based on Microalgal Biomass for Intestinal Diseases Treatment. Science Advances 2021, 7(48): eabi9265. (Front Cover PaperHighlighted: Nature Medicine 2022, 28(6): 1100-1102.

43. Zhao H, Xu J, Feng C, Ren J, Bao L, Zhao Y, Tao W*, Zhao Y, Yang X. Tailoring Aggregation Extent of Photosensitizer to Boost Phototherapy Potency for Eliciting Systemic Antitumor Immunity. Advanced Materials 2022, 34(8): e2106390. (Web of Science Highly Cited Paper)

42. Singh N, Son S, An J, Kim I, Choi M, Kong N, Tao W*, Kim JS. Nanoscale porous organic polymers for drug delivery and advanced cancer theranostics. Chemical Society Reviews 2021, 50(23): 12883-12896.

41. Zhou J, Zhang Z, Joseph J, Zhang X, Ferdows BE, Patel DN, Chen W, Banfi G, Molinaro R, Cosco D, Kong N, Joshi N, Farokhzad OC, Corbo C, Tao W*. Biomaterials and Nanomedicine for Bone Regeneration: Progress and Future Prospects. Exploration 2021, 1(2): 20210011. (Front Cover Paper) (Invited Article)

40. Li S, Wang L, Gu Y, Lin L, Zhang M, Jin M, Mao C, Zhou J, Zhang W, Huang X, Corbo C, Tao W*, Lu E, Liu J. Biomimetic immunomodulation by crosstalk with nanoparticulate regulatory T cells. Matter (Cell Press) 2021, 4(11): 3621-3645.

39. Tao W*, Farokhzad OC. Theranostic Nanomedicine in the NIR-II Window: Classification, Fabrication, and Biomedical Applications. Chemical Reviews 2022, 122(6): 5405-5407. (Invited Article)

38. Xiao Y, Tang Z, Huang X, Joseph J, Chen W, Liu C, Zhou J, Kong N, Joshi N, Du J, Tao W*. Glucose-responsive oral insulin delivery platform for one-treatment-a-day in diabetes. Matter (Cell Press) 2021, 4(10): 3269–3285. Highlighted: Matter, 2021, 4(12): 3790-3791.

37. Kong N, Zhang H, Feng C, Liu C, Xiao Y, Zhang X, Mei L, Kim JS, Tao W*, Ji X. Arsenene-mediated multiple independently targeted reactive oxygen species burst for cancer therapy. Nature Communications 2021, 12: 4777. Highlighted: Nature Portfolio | Bioengineering Community (Web of Science Hot Paper | Highly Cited Paper)

36. Zhang X, Li L, Ouyang J, Zhang L, Xue J, Zhang H, Tao W*. Electroactive electrospun nanofibers for tissue engineering. Nano Today 2021, 39: 101196. (Web of Science Highly Cited Paper)

35. Zhang X, Koo S, Kim JH, Huang X, Kong N, Zhang L, Zhou J, Xue J, Harris MB, Tao W*, Kim JS. Nanoscale Materials-Based Platforms for the Treatment of Bone-Related Diseases. Matter (Cell Press) 2021, 4(9): 2727-2764.

34. Liu C, Sun S, Feng Q, Wu G, Wu Y, Kong N, Yu Z, Yao J, Zhang X, Chen W, Tang Z, Xiao Y, Huang X, Lv A, Yao C, Cheng H, Wu A, Xie T, Tao W*. Arsenene Nanodots with Selective Killing Effects and their Low-Dose Combination with ß-Elemene for Cancer Therapy. Advanced Materials 2021, 33(37): 2102054. (Frontispiece Cover Paper; Web of Science Hot Paper | Highly Cited Paper)

33. Ouyang J, Feng C, Zhang X, Kong N, Tao W*. Black Phosphorus in Biomedical Applications: Evolutionary Journey from Monoelemental Materials to Composite Materials. Accounts of Materials Research 2021, 2(7): 489–500. (ACS Editors' Choice Featured; Front Cover Paper)

32. Farokhzad N, Tao W*. Materials Chemistry-Enabled Platforms in Detecting Sexually Transmitted Infections: Progress towards Point-of-Care Tests. Trends in Chemistry (Cell Press) 2021, 3(7): 589-602. (Invited Article

31. Zhang X, Duan X, Hu Y, Tang Z, Miao C, Tao W*, Wu J. One-step and facile synthesis of peptide-like poly(melphalan) nanodrug for cancer therapy. Nano Today 2021, 37:101098. (Web of Science Highly Cited Paper)

30. Ji X, Ge L, Liu C, Tang Z, Xiao Y, Chen W, Lei Z, Gao W, Blake S, De D, Shi B, Zeng X, Kong N, Zhang X, Tao W*. Capturing functional two-dimensional nanosheets from sandwich-structure vermiculite for cancer theranostics. Nature Communications 2021, 12: 1124. Highlighted: Nature Portfolio | Bioengineering Community (Web of Science Hot Paper | Highly Cited Paper)

29. Liu C, Shin J, Son S, Choe Y, Farokhzad N, Tang Z, Xiao Y, Kong N, Xie T, Kim JS, Tao W*. Pnictogens in Medicinal Chemistry: Evolution from Erstwhile Drugs to Emerging Layered Photonic Nanomedicine. Chemical Society Reviews 2021, 50(4): 2260-2279. (Web of Science Highly Cited Paper)

28. Chen W, Liu C, Ji X, Joseph J, Tang Z, Ouyang J, Xiao Y, Kong N, Joshi N, Farokhzad OC, Tao W*, Xie T. Stanene-Based Nanosheets for ß-Elemene Delivery and Ultrasound-Mediated Combination Cancer Therapy. Angewandte Chemie International Edition 2021, 60(13): 7155-7164. (Angew. Chem. VIP and Front Cover Paper; Web of Science Highly Cited Paper

27. Yang J, Zhang X, Liu C, Wang Z, Deng L, Feng C, Tao W*, Xu X, Cui W. Biologically Modified Nanoparticles as Theranostic Bionanomaterials. Progress in Materials Science 2021, 118: 100768. 

26. Tang Z, Zhang X, Shu Y, Guo M, Zhang H, Tao W*. Insights from nanotechnology in COVID-19 treatment. Nano Today 2021, 36:101019. (Most Downloaded Nano Today Articles - TOP 2; Web of Science Highly Cited Paper

25. Liu Y, Wang J, Xiong Q, Hornburg D, Tao W*, Farokhzad OC. Nano-Bio Interactions in Cancer: from Therapeutics Delivery to Early Detection. Accounts of Chemical Research 2021, 54(2): 291–301. (Cover Paper; Web of Science Highly Cited Paper) (Invited Article

2020

24. Zhang Z, Tang Z, Farokhzad N, Chen T, Tao W*. Sensitive, Rapid, Low-cost and Multiplexed COVID-19 Monitoring by the Wireless Telemedicine Platform. Matter (Cell Press) 2020, 3(6): 1818-1820. (Invited Article)

23. Ouyang J, Ji X, Zhang X, Feng C, Tang Z, Kong N, Xie A, Wang J, Sui X, Deng L, Liu Y, Kim JS, Cao Y, Tao W*. In situ sprayed NIR-responsive, analgesic black phosphorus-based gel for diabetic ulcer treatment. Proceedings of the National Academy of Sciences USA 2020, 117(46): 28667-28677 (PNAS Direct Submission). (Web of Science Highly Cited PaperHighlighted: Materials Research Society (MRS) Bulletin Materials News (MRS Bulletin 2021, 46(3): 199)

22. Tang Z, Kong N, Zhang X, Liu Y, Hu P, Mou S, Liljeström P, Shi J, Tan W, Kim JS, Cao Y, Langer R, Leong K, Farokhzad OC, Tao W*. A materials science perspective on tackling COVID-19. Nature Reviews Materials 2020, 5(11): 847-860. (Front Cover Paper; Web of Science Highly Cited PaperHighlighted: Nature Portfolio | Bioengineering CommunityNature Materials 2022, 21, 609.

21. Huang W, He L, Ouyang J, Chen Q, Liu C, Tao W*, Chen T. Triangle-Shaped Tellurium Nanostars Potentiate Radiotherapy by Boosting Checkpoint Blockade Immunotherapy. Matter (Cell Press) 2020, 3(5): 1725-1753.

20. Ouyang J, Tang Z, Farokhzad N, Kong N, Kim NY, Feng C, Blake S, Xiao Y, Liu C, Xie T, Tao W*. Ultrasound Mediated Therapy: Recent Progress and Challenges in Nanoscience. Nano Today 2020, 35: 100949. 

19. Xiao Y, Tang Z, Wang J, Liu C, Kong N, Farokhzad OC, Tao W*. Oral insulin delivery platforms: Strategies to address the biological barriers. Angewandte Chemie International Edition 2020, 59(45): 19787-19795. (Angew. Chem. VIP and Cover Paper) (Invited Article

18. Tao W, Yurdagul A, Kong N, Li W, Wang X, Doran A, Feng C, Wang J, Islam MA, Farokhzad OC, Tabas I, Shi J. siRNA nanoparticles targeting CaMKIIγ in lesional macrophages improve atherosclerotic plaque stability in mice. Science Translational Medicine 2020, 12(553): eaay1063. (Front Cover PaperHighlighted: Nature Reviews Cardiology 2020, 17(10): 612; Matter (Cell Press) 2020, 3(3): 621-622

17. Hu K, Xie L, Zhang Y, Hanyu M, Yang Z, Nagatsu K, Suzuki H, Ouyang J, Ji X, Wei J, Xu H, Farokhzad OC, Liang SH, Wang L, Tao W*, Zhang MR. Marriage of black phosphorus and Cu2+ as effective photothermal agents for PET-guided combination cancer therapy. Nature Communications 2020, 11(1): 2778. (Web of Science Highly Cited Paper

16. Feng C, Ouyang J, Tang Z, Kong N, Liu Y, Fu L, Ji X, Xie T, Farokhzad OC, Tao W*. Germanene-based Theranostic Materials for Surgical Adjuvant Treatment: Inhibiting Tumor Recurrence and Wound Infection. Matter (Cell Press) 2020, 3(1): 127-144. (Front Cover Paper; Web of Science Highly Cited Paper; Selected in “Matter - Most Cited ArticlesHighlighted: Matter (Cell Press), 2020, 3(1): 12-13

15. Kong N, Ji X, Wang J, Sun X, Chen G, Fan T, Liang W, Zhang H, Xie A, Farokhzad OC, Tao W*. ROS-Mediated Selective Killing Effect of Black Phosphorus: Mechanistic Understanding and Its Guidance for Safe Biomedical Applications. Nano Letters 2020, 20(5): 3943-3955. (Web of Science Highly Cited Paper

14. Tang Z, Kong N, Ouyang J, Feng C, Kim NY, Ji X, Wang C, Farokhzad OC, Zhang H, Tao W*. Phosphorus Science oriented Design and Synthesis of Multifunctional Nanomaterials for Biomedical Applications. Matter (Cell Press) 2020, 2(2): 297-322. (Web of Science Highly Cited Paper; Selected in “Matter - Most Cited Articles

13. Ji X, Kang Y, Fan T, Xiong Q, Zhang S, Tao W*, Zhang H. An antimonene/Cp* Rh (phen) Cl/black phosphorus hybrid nanosheet-based Z-scheme artificial photosynthesis for enhanced photo/bio-catalytic CO2 reduction. Journal of Materials Chemistry A 2020, 8(1): 323-333. 

Before 2019

12. Kong N#, Tao W#,*, Ling X, Wang J, Xiao Y, Shi S, Ji X, Shajii A, Gan ST, Kim NY, Duda DG, Xie T, Farokhzad OC, Shi J. Synthetic mRNA nanoparticle-mediated restoration of p53 tumor suppressor sensitizes p53-deficient cancers to mTOR inhibition. Science Translational Medicine 2019, 11(523): eaaw1565. Highlighted: F1000Prime Recommendation - Rated Very Good

11. Ji X, Kang Y, Ouyang J, Chen Y, Zeng X, Xiao Y, Feng C, Qi B, Kim N, Saw P, Farokhzad OC, Tao W*. Synthesis of Ultrathin Biotite Nanosheets as an Intelligent Theranostic Platform for Combination Cancer Therapy. Advanced Science 2019, 6(19): 1901211. (Cover Paper; Web of Science Highly Cited Paper

10. Ouyang J, Feng C, Ji X, Li L, Gutti HK, Kim NY, Artzi D, Xie A, Kong N, Liu YN, Tearney GJ, Sui X, Tao W*, Farokhzad OC. 2D Monoelemental Germanene Quantum Dots: Synthesis as Robust Photothermal Agents for Photonic Cancer Nanomedicine. Angewandte Chemie International Edition 2019, 58(38): 13405-13410. 

9. Tao W*, Kong N, Ji X, Zhang Y, Sharma A, Ouyang J, Qi B, Wang J, Xie N, Kang C, Zhang H, Farokhzad OC, Kim JS. Emerging two-dimensional monoelemental materials (Xenes) for biomedical applications. Chemical Society Reviews 2019, 48(11): 2891-2912. (Front Cover Paper; Web of Science Hot Paper | Highly Cited Paper)  

8. Tao W*, Wang J, Parak W, Farokhzad OC, Shi J. Nanobuffering of pH-Responsive Polymers: A Known but Sometimes Overlooked Phenomenon and its Biological Applications. ACS Nano 2019, 13(5): 4876-4882. (Invited Article

7. Ling X, Tu J, Wang J, Shajii A, Kong N, Feng C, Zhang Y, Yu M, Xie T, Bharwani Z, Aljaeid BM, Shi B, Tao W*, Farokhzad OC. Glutathione-Responsive Prodrug Nanoparticles for Effective Drug Delivery and Cancer Therapy. ACS Nano 2019, 13(1): 357-370. (Cover Paper; Web of Science Highly Cited Paper

6. Islam MA#, Xu Y#, Tao W# (equal contribution), Ubellacker JM, Lim M, Aum D, Lee GY, Zhou K, Zope H, Yu M, Cao W, Oswald JT, Dinarvand M, Mahmoudi M, Langer R, Kantoff PW, Farokhzad OC, Zetter BR, Shi J. Restoration of tumour-growth suppression in vivo via systemic nanoparticle-mediated delivery of PTEN mRNA. Nature Biomedical Engineering 2018, 2(11): 850-864. (Highlighted in the "Delivery of drugs and biologics" Collection from Nature Biomedical Engineering)

5. Tao W, Ji X, Zhu X, Li L, Wang J, Zhang Y, Saw PE, Li W, Kong N, Islam MA, Gan T, Zeng X, Zhang H, Mahmoudi M, Tearney GJ, Farokhzad OC. Two-Dimensional Antimonene-based Photonic Nanomedicine for Cancer Theranostics. Advanced Materials 2018, 30(38): 1802061. (Cover Paper; Web of Science Highly Cited Paper

4. Rosenblum D#, Joshi N#, Tao W# (equal contribution), Karp JM, Peer D. Progress and challenges towards targeted delivery of cancer therapeutics. Nature Communications 2018, 9(1): 1410. (Web of Science Hot Paper | Highly Cited Paper)

3. Zhu X, Ji X, Kong N, Chen Y, Mahmoudi M, Xu X, Ding L, Tao W*, Cai T, Li Y, Gan T, Barrett A, Bharwani Z, Chen H, Farokhzad OC. Intracellular Mechanistic Understanding of 2D MoS2 Nanosheets for Anti-Exocytosis Enhanced Synergistic Cancer Therapy. ACS Nano 2018, 12(3): 2922–2938. (Web of Science Highly Cited Paper

2. Tao W, Ji X, Xu X, Ariful IM, Li Z, Chen S, Saw PE, Zhang H, Bharwani Z, Guo Z, Shi J, Farokhzad OC. Antimonene Quantum Dots: Synthesis and Application as Near-Infrared Photothermal Agents for Effective Cancer Therapy. Angewandte Chemie International Edition 2017, 56(39): 11896-11900. (Cover Paper; Web of Science Highly Cited Paper

1. Tao W, Zhu X, Yu X, Zeng X, Xiao Q, Zhang X, Wang X, Ji X, Shi J, Zhang H, Mei L. Black Phosphorus Nanosheets as a Robust Delivery Platform for Cancer Theranostics. Advanced Materials 2017, 29(1): 1603276. (Cover Paper; Web of Science Hot Paper | Highly Cited Paper